Divalproex is an inhibitor of the enzyme called histone deacetylase 1 (HDAC1). HDAC1 is needed for HIV to remain in infected cells. A study published in August 2005 revealed that patients treated with valproic acid (divalproex) in addition to highly active antiretroviral therapy (HAART) showed a 75% reduction in latent HIV infection. This may one day lead to a cure for HIV and AIDS.

Another potential indication may be for the treatment of leukemia in juvenile patients. Studies conducted by several European centres are ongoing and, although it is too early to make a definitive statement, preliminary results are encouraging.

 

FDA Information

Why is this medication prescribed?

Dosage and using this medicine

What special precautions should I follow?

What should I do if I forget a dose?

What side effects can this medication cause?

What storage conditions are needed for this medicine?

In case of an emergency/overdose